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Down-regulation of argininosuccinate synthetase is associated with  cisplatin resistance in hepatocellular carcinoma cell lines: implications  for PEGylated arginine deiminase combination therapy | BMC Cancer | Full  Text
Down-regulation of argininosuccinate synthetase is associated with cisplatin resistance in hepatocellular carcinoma cell lines: implications for PEGylated arginine deiminase combination therapy | BMC Cancer | Full Text

Molecules | Free Full-Text | Arginine Deiminase Induces Immunogenic Cell  Death and Is Enhanced by N-acetylcysteine in Murine MC38 Colorectal Cancer  Cells and MDA-MB-231 Human Breast Cancer Cells In Vitro
Molecules | Free Full-Text | Arginine Deiminase Induces Immunogenic Cell Death and Is Enhanced by N-acetylcysteine in Murine MC38 Colorectal Cancer Cells and MDA-MB-231 Human Breast Cancer Cells In Vitro

Depleting arginine as a first-line cancer therapy
Depleting arginine as a first-line cancer therapy

A phase 1 study of ADI-PEG 20 and modified FOLFOX6 in patients with  advanced hepatocellular carcinoma and other gastrointestinal malignancies |  SpringerLink
A phase 1 study of ADI-PEG 20 and modified FOLFOX6 in patients with advanced hepatocellular carcinoma and other gastrointestinal malignancies | SpringerLink

Pegylated Arginine Deiminase Downregulates Colitis in Murine Models
Pegylated Arginine Deiminase Downregulates Colitis in Murine Models

A randomised phase II study of pegylated arginine deiminase (ADI-PEG 20) in  Asian advanced hepatocellular carcinoma patients | British Journal of Cancer
A randomised phase II study of pegylated arginine deiminase (ADI-PEG 20) in Asian advanced hepatocellular carcinoma patients | British Journal of Cancer

Pegylated arginine deiminase drives arginine turnover and systemic  autophagy to dictate energy metabolism
Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism

Experimental Cancer Drug Mimics Beneficial Fasting Effects
Experimental Cancer Drug Mimics Beneficial Fasting Effects

Phase 1b study of pegylated arginine deiminase (ADI-PEG 20) plus  Pembrolizumab in advanced solid cancers
Phase 1b study of pegylated arginine deiminase (ADI-PEG 20) plus Pembrolizumab in advanced solid cancers

提前報喜! 北極星(6550) ADI-PEG20肺間皮癌三期試驗數據亮眼將陸續向美國FDA和歐盟討論藥證申請- 生技投資第一站-Genet 觀點
提前報喜! 北極星(6550) ADI-PEG20肺間皮癌三期試驗數據亮眼將陸續向美國FDA和歐盟討論藥證申請- 生技投資第一站-Genet 觀點

Polaris says new cancer treatment passes clinical trials - Taipei Times
Polaris says new cancer treatment passes clinical trials - Taipei Times

ADI-PEG 20 reduces B16-F10 tumor growth as a single agent and in... |  Download Scientific Diagram
ADI-PEG 20 reduces B16-F10 tumor growth as a single agent and in... | Download Scientific Diagram

Molecules | Free Full-Text | Arginine Deiminase Induces Immunogenic Cell  Death and Is Enhanced by N-acetylcysteine in Murine MC38 Colorectal Cancer  Cells and MDA-MB-231 Human Breast Cancer Cells In Vitro
Molecules | Free Full-Text | Arginine Deiminase Induces Immunogenic Cell Death and Is Enhanced by N-acetylcysteine in Murine MC38 Colorectal Cancer Cells and MDA-MB-231 Human Breast Cancer Cells In Vitro

A randomised phase II study of pegylated arginine deiminase (ADI-PEG 20) in  Asian advanced hepatocellular carcinoma patients | British Journal of Cancer
A randomised phase II study of pegylated arginine deiminase (ADI-PEG 20) in Asian advanced hepatocellular carcinoma patients | British Journal of Cancer

A trial of a new drug called ADI-PEG 20 with chemotherapy for people with  mesothelioma (ATOMIC-Meso) | Cancer Research UK
A trial of a new drug called ADI-PEG 20 with chemotherapy for people with mesothelioma (ATOMIC-Meso) | Cancer Research UK

Polaris Group Lead Therapeutic Candidate ADI-PEG 20 Receives Orphan Drug  Designation in the United States and the European Union for the Treatment  of Malignant Pleural Mesothelioma
Polaris Group Lead Therapeutic Candidate ADI-PEG 20 Receives Orphan Drug Designation in the United States and the European Union for the Treatment of Malignant Pleural Mesothelioma

北極星新藥,獲邀世界肺癌大會發表論文| TechNews 科技新報
北極星新藥,獲邀世界肺癌大會發表論文| TechNews 科技新報

Pegylated arginine deiminase drives arginine turnover and systemic  autophagy to dictate energy metabolism - ScienceDirect
Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism - ScienceDirect

Model of [ 18 F]AFETP uptake in response to ADI-PEG20 treatment. In the...  | Download Scientific Diagram
Model of [ 18 F]AFETP uptake in response to ADI-PEG20 treatment. In the... | Download Scientific Diagram

北極星ADI-PEG 20臨床試驗結果優力拚成為肝癌一線標準療法| Anue鉅亨- 台股新聞
北極星ADI-PEG 20臨床試驗結果優力拚成為肝癌一線標準療法| Anue鉅亨- 台股新聞

Apoptosis induction by ADI-PEG 20 in resistant and sensitive AML in... |  Download Scientific Diagram
Apoptosis induction by ADI-PEG 20 in resistant and sensitive AML in... | Download Scientific Diagram

Molecules | Free Full-Text | Arginine Deiminase Induces Immunogenic Cell  Death and Is Enhanced by N-acetylcysteine in Murine MC38 Colorectal Cancer  Cells and MDA-MB-231 Human Breast Cancer Cells In Vitro
Molecules | Free Full-Text | Arginine Deiminase Induces Immunogenic Cell Death and Is Enhanced by N-acetylcysteine in Murine MC38 Colorectal Cancer Cells and MDA-MB-231 Human Breast Cancer Cells In Vitro

Pegargiminase
Pegargiminase

Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates  Survival through General Control Nonderepressible 2 Kinase–Mediated  Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated  Arginine Deiminase - ScienceDirect
Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase–Mediated Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated Arginine Deiminase - ScienceDirect

北極星藥業(6550) - Warburg effect and ADI-PEG 20.jpg @ 穿夾腳拖的老黑胖的相簿:: 痞客邦::
北極星藥業(6550) - Warburg effect and ADI-PEG 20.jpg @ 穿夾腳拖的老黑胖的相簿:: 痞客邦::

Role of 3'-Deoxy-3'-[18F] Fluorothymidine Positron Emission  Tomography-Computed Tomography as a Predictive Biomarker in  Argininosuccinate Synthetase 1-Deficient Thoracic Cancers Treated With  Pegargiminase - JTO Clinical and Research Reports
Role of 3'-Deoxy-3'-[18F] Fluorothymidine Positron Emission Tomography-Computed Tomography as a Predictive Biomarker in Argininosuccinate Synthetase 1-Deficient Thoracic Cancers Treated With Pegargiminase - JTO Clinical and Research Reports

Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates  Survival through General Control Nonderepressible 2 Kinase–Mediated  Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated  Arginine Deiminase - ScienceDirect
Argininosuccinate Synthetase 1 Loss in Invasive Bladder Cancer Regulates Survival through General Control Nonderepressible 2 Kinase–Mediated Eukaryotic Initiation Factor 2α Activity and Is Targetable by Pegylated Arginine Deiminase - ScienceDirect